The first thing I do, with a new computer, before I deliver it to the user is remove all stickers. They annoy the hell out of me!
Rip-off? It has its own "glass" look, the close, maximise and minimise buttons are on the right and Windows Search (Spotlight equivalent) is at the bottom left, not top right) in the Windows menu (think an intelligent stack into the "Application" folder on the dock). Menu bars are anchored to the applications, not the top of the screen.
But in actual use, they are very close. You can drag and drop applications or documents onto the Task Bar, in the same way as you do with the Dock. If you can use Finder, you can use Windows Explorer to copy files... Other than that, neither really get in the way of you using your applications.
At the end of the day, it is the applications which shape how you work with the computer. The operating system needs to make it easy for the user to launch the application, then get the hell out of the way and let the user get on with using their application(s).
I switch between Win 7 and OS X several times a day, and I really don't have to think about it, I just click on the app icon I need and start working. I have them set up in a simiular order on the Task Bar and Dock and that's it.
The only time you really see a big difference is when you need to install a new piece of hardware, but both make the process relatively easy.