Just ran a report, not sure whether I ran the right version or not(?) as I am on Windows 7, any have any ideas if anything is wrong (well.. missing files aside by the looks of it..)

gfile of Trend Micro HijackThis v2.0.2
Scan saved at 19:41:41, on 25/09/2010
Platform: Unknown Windows (WinNT 6.01.3504)
MSIE: Internet Explorer v8.00 (8.00.7600.16385)
Boot mode: Safe mode with network support

Running processes:
C:\Program Files (x86)\Trend Micro\HijackThis\HijackThis.exe
C:\Program Files (x86)\Mozilla Firefox\firefox.exe
C:\Program Files (x86)\Mozilla Firefox\plugin-container.exe
C:\Program Files (x86)\Microsoft Office\Office12\OUTLOOK.EXE

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Local Page = C:\Windows\SysWOW64\blank.htm
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
F2 - REG:system.ini: UserInit=userinit.exe
O2 - BHO: AcroIEHelperStub - {18DF081C-E8AD-4283-A596-FA578C2EBDC3} - C:\Program Files (x86)\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelperShim.dll
O2 - BHO: IEVkbdBHO - {59273AB4-E7D3-40F9-A1A8-6FA9CCA1862C} - C:\Program Files (x86)\Kaspersky Lab\Kaspersky Anti-Virus 2011\ievkbd.dll
O2 - BHO: (no name) - {5C255C8A-E604-49b4-9D64-90988571CECB} - (no file)
O2 - BHO: Windows Live Sign-in Helper - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files (x86)\Common Files\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O2 - BHO: SkypeIEPluginBHO - {AE805869-2E5C-4ED4-8F7B-F1F7851A4497} - C:\Program Files (x86)\Skype\Toolbars\Internet Explorer\skypeieplugin.dll
O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - C:\Program Files (x86)\Java\jre6\bin\jp2ssv.dll
O2 - BHO: link filter bho - {E33CF602-D945-461A-83F0-819F76A199F8} - C:\Program Files (x86)\Kaspersky Lab\Kaspersky Anti-Virus 2011\klwtbbho.dll
O4 - HKLM\..\Run: [AVP] "C:\Program Files (x86)\Kaspersky Lab\Kaspersky Anti-Virus 2011\avp.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files (x86)\Common Files\Java\Java Update\jusched.exe"
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files (x86)\QuickTime\QTTask.exe" -atboottime
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files (x86)\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "C:\Program Files (x86)\Adobe\Reader 9.0\Reader\Reader_sl.exe"
O4 - HKLM\..\Run: [Adobe ARM] "C:\Program Files (x86)\Common Files\Adobe\ARM\1.0\AdobeARM.exe"
O4 - HKLM\..\Run: [SPIRunE] Rundll32 SPIRunE.dll,RunDLLEntry
O4 - HKCU\..\Run: [Sidebar] C:\Program Files\Windows Sidebar\sidebar.exe /autoRun
O4 - HKUS\S-1-5-19\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /autoRun (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-19\..\RunOnce: [mctadmin] C:\Windows\System32\mctadmin.exe (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /autoRun (User 'NETWORK SERVICE')
O4 - HKUS\S-1-5-20\..\RunOnce: [mctadmin] C:\Windows\System32\mctadmin.exe (User 'NETWORK SERVICE')
O4 - Global Startup: Audible Download Manager.lnk = C:\Program Files (x86)\Audible\Bin\AudibleDownloadHelper.exe
O4 - Global Startup: Logitech SetPoint.lnk = ?
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~2\MICROS~1\Office12\EXCEL.EXE/3000
O9 - Extra button: &Virtual Keyboard - {4248FE82-7FCB-46AC-B270-339F08212110} - C:\Program Files (x86)\Kaspersky Lab\Kaspersky Anti-Virus 2011\klwtbbho.dll
O9 - Extra button: Skype add-on for Internet Explorer - {898EA8C8-E7FF-479B-8935-AEC46303B9E5} - C:\Program Files (x86)\Skype\Toolbars\Internet Explorer\skypeieplugin.dll
O9 - Extra 'Tools' menuitem: Skype add-on for Internet Explorer - {898EA8C8-E7FF-479B-8935-AEC46303B9E5} - C:\Program Files (x86)\Skype\Toolbars\Internet Explorer\skypeieplugin.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~2\MICROS~1\Office12\REFIEBAR.DLL
O9 - Extra button: URLs c&heck - {CCF151D8-D089-449F-A5A4-D9909053F20F} - C:\Program Files (x86)\Kaspersky Lab\Kaspersky Anti-Virus 2011\klwtbbho.dll
O13 - Gopher Prefix:
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload2.macromedia.com/get/s ... wflash.cab
O18 - Protocol: skype-ie-addon-data - {91774881-D725-4E58-B298-07617B9B86A8} - C:\Program Files (x86)\Skype\Toolbars\Internet Explorer\skypeieplugin.dll
O18 - Protocol: skype4com - {FFC8B962-9B40-4DFF-9458-1830C7DD7F5D} - C:\PROGRA~2\COMMON~1\Skype\SKYPE4~1.DLL
O20 - AppInit_DLLs: ,C:\PROGRA~2\KASPER~1\KASPER~1\mzvkbd3.dll
O23 - Service: @%SystemRoot%\system32\Alg.exe,-112 (ALG) - Unknown owner - C:\Windows\System32\alg.exe (file missing)
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files (x86)\Common Files\Apple\Mobile Device Support\AppleMobileDeviceService.exe
O23 - Service: Kaspersky Anti-Virus Service (AVP) - Kaspersky Lab ZAO - C:\Program Files (x86)\Kaspersky Lab\Kaspersky Anti-Virus 2011\avp.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files (x86)\Bonjour\mDNSResponder.exe
O23 - Service: Creative Audio Engine Licensing Service - Creative Labs - C:\Program Files (x86)\Common Files\Creative Labs Shared\Service\CTAELicensing.exe
O23 - Service: Creative Audio Service (CTAudSvcService) - Creative Technology Ltd - C:\Program Files (x86)\Creative\Shared Files\CTAudSvc.exe
O23 - Service: Dragon Age: Origins - Content Updater (DAUpdaterSvc) - BioWare - c:\program files (x86)\steam\steamapps\common\dragon age origins\bin_ship\DAUpdaterSvc.Service.exe
O23 - Service: @%SystemRoot%\system32\efssvc.dll,-100 (EFS) - Unknown owner - C:\Windows\System32\lsass.exe (file missing)
O23 - Service: @%systemroot%\system32\fxsresm.dll,-118 (Fax) - Unknown owner - C:\Windows\system32\fxssvc.exe (file missing)
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: @keyiso.dll,-100 (KeyIso) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: Logitech Bluetooth Service (LBTServ) - Logitech, Inc. - C:\Program Files\Common Files\Logitech\Bluetooth\LBTServ.exe
O23 - Service: @comres.dll,-2797 (MSDTC) - Unknown owner - C:\Windows\System32\msdtc.exe (file missing)
O23 - Service: @%SystemRoot%\System32\netlogon.dll,-102 (Netlogon) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: NVIDIA Display Driver Service (nvsvc) - Unknown owner - C:\Windows\system32\nvvsvc.exe (file missing)
O23 - Service: PnkBstrA - Unknown owner - C:\Windows\system32\PnkBstrA.exe
O23 - Service: @%systemroot%\system32\psbase.dll,-300 (ProtectedStorage) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%systemroot%\system32\Locator.exe,-2 (RpcLocator) - Unknown owner - C:\Windows\system32\locator.exe (file missing)
O23 - Service: @%SystemRoot%\system32\samsrv.dll,-1 (SamSs) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%SystemRoot%\system32\snmptrap.exe,-3 (SNMPTRAP) - Unknown owner - C:\Windows\System32\snmptrap.exe (file missing)
O23 - Service: @%systemroot%\system32\spoolsv.exe,-1 (Spooler) - Unknown owner - C:\Windows\System32\spoolsv.exe (file missing)
O23 - Service: @%SystemRoot%\system32\sppsvc.exe,-101 (sppsvc) - Unknown owner - C:\Windows\system32\sppsvc.exe (file missing)
O23 - Service: Steam Client Service - Valve Corporation - C:\Program Files (x86)\Common Files\Steam\SteamService.exe
O23 - Service: @%SystemRoot%\system32\ui0detect.exe,-101 (UI0Detect) - Unknown owner - C:\Windows\system32\UI0Detect.exe (file missing)
O23 - Service: @%SystemRoot%\system32\vaultsvc.dll,-1003 (VaultSvc) - Unknown owner - C:\Windows\system32\lsass.exe (file missing)
O23 - Service: @%SystemRoot%\system32\vds.exe,-100 (vds) - Unknown owner - C:\Windows\System32\vds.exe (file missing)
O23 - Service: @%systemroot%\system32\vssvc.exe,-102 (VSS) - Unknown owner - C:\Windows\system32\vssvc.exe (file missing)
O23 - Service: @%SystemRoot%\system32\Wat\WatUX.exe,-601 (WatAdminSvc) - Unknown owner - C:\Windows\system32\Wat\WatAdminSvc.exe (file missing)
O23 - Service: @%systemroot%\system32\wbengine.exe,-104 (wbengine) - Unknown owner - C:\Windows\system32\wbengine.exe (file missing)
O23 - Service: @%Systemroot%\system32\wbem\wmiapsrv.exe,-110 (wmiApSrv) - Unknown owner - C:\Windows\system32\wbem\WmiApSrv.exe (file missing)
O23 - Service: @%PROGRAMFILES%\Windows Media Player\wmpnetwk.exe,-101 (WMPNetworkSvc) - Unknown owner - C:\Program Files (x86)\Windows Media Player\wmpnetwk.exe (file missing)

Am not used to Win7, but essentially nothing obviously worrying.

Any reason to run hijackthis?

I'm sure someone more experienced will come along and have a look. I'd recommend googling each process eg alg.exe (which is normal if it's in the right place) to have a look for threats.

Ok, thanks.

Reason is my PC is still dying for no reason, having checked all connections, all drivers, all programs, still getting periodic BSODs.

What problems are you getting exactly?