+1 for Carbon Copy Cloner...
http://www.bombich.comNo obligation to donate, except for that warm feeling - personally I've used it a lot so I've donated, but it works fine without having to part with any cash.
Will take a few hours to clone, before setting it running check the following on the Mac...
1. It's plugged into a power source, obviously - otherwise it's shut down when the battery runs out!
2. Check Energy Saver options are set so it doesn't automatically go to sleep
System Preferences > Energy Saver (you can set the display to sleep if you like, just pull the other slider to "Never" and un-tick "Put the hard disk(s) to sleep when possible" check box)
Once completed, swap drives, put the old one into the enclosure and connect - then restart with the "Alt" key held down, where you can select the external drive (the old one) to boot from. Launch Disk Utility, select the new drive and format it by going to the "Partition" tab - select the Options button and select the "GUID Partition Scheme" option. OK that, then select "One Partition" in the drop down menu, making sure it's set to
"Mac OS Extended (Journalled)" - click Apply and it'll erase and re-partition the drive for Intel Macs to boot from.
Then, once you've erased the new drive (the internal one), run Carbon Copy Cloner again from the external drive - clone the external across to the internal one and once finished go to
System Preference > Startup Disk and make the internal one the default boot drive. Restart, and all should be back to normal - except you'll have more free space on the drive.
Certain software might detect a change of hardware configuration - for example, QuarkXpress does - in which case you may need to re-activate it. Most software will run just as before though.
EDIT: I've done it the other way round than you originally said, but it'll work that way too (i.e. clone first to new drive in enclosure, then swap drives over) - just remember to erase the new drive first using Disk Utility and to use the "GUID Partition Scheme" option - otherwise Intel Macs like the Macbook might not be able to boot from it.